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FISH for Pre-implantation Genetic Diagnosis
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Assignment of the human GATA4 gene to 8p23.1-->p22 using fluorescence in situ hybridization analysis
W Y Huang1, H H Heng, C C Liew
1Department of Clinical Biochemistry, Toronto Hospital, University of Toronto, Ont., Canada.
Cytogenetics and Cell Genetics
|January 1, 1996
Abstract:
Using fluorescence in situ hybridization, the human GATA4 gene, a member of the zinc-finger protein family recognizing the consensus GATA motif, was mapped to 8p23.1-->p22. This result, in conjunction with gene mapping data on other GATA-DNA binding proteins, suggests that genes encoding GATA-DNA binding proteins are dispersed throughout the genome, rather than clustered within a single locus.
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