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Adequacy of peritoneal dialysis
1Division of Nephrology, London Health Sciences Centre, Ontario, Canada.
Current Opinion in Nephrology and Hypertension
|November 1, 1996
Summary
Recent studies on peritoneal dialysis adequacy show clearance indices link to survival, but residual kidney function confounds results. Dialysis survival rates remain debated, and malnutrition causes are increasingly understood.
Area of Science:
- Nephrology
- Renal Medicine
- Dialysis Therapy
Background:
- Landmark studies on peritoneal dialysis (PD) adequacy have been published.
- Previous research indicates a link between clearance indices and patient survival in PD.
- Conflicting registry data exist regarding survival rates between peritoneal dialysis and hemodialysis.
Purpose of the Study:
- To review recent findings on peritoneal dialysis adequacy.
- To discuss the relationship between clearance indices and survival in PD.
- To highlight the complexities of malnutrition in dialysis patients.
Main Methods:
- Analysis of landmark studies on dialysis adequacy.
- Review of Canada/USA peritoneal dialysis study findings.
- Examination of registry data comparing PD and hemodialysis survival.
Main Results:
- The Canada/USA peritoneal dialysis study suggests clearance indices correlate with survival, though residual renal function is a confounding factor.
- Registry data present conflicting outcomes on survival rates between PD and hemodialysis.
- The complex mechanisms underlying malnutrition in dialysis patients are gaining recognition.
Conclusions:
- Peritoneal dialysis adequacy and patient survival require further investigation, considering confounding factors like residual renal function.
- Comparative survival data between PD and hemodialysis remain inconclusive.
- Understanding and addressing malnutrition in dialysis patients is crucial.