Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Infection and prematurity: evidence-based approaches

J A McGregor1, J I French, S Witkin

  • 1Department of Obstetrics and Gynecology, University of Colorado Health Sciences Center, Denver 80262, USA.

Current Opinion in Obstetrics & Gynecology
|December 1, 1996
PubMed
Summary

Preventing preterm birth from infections saves children

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pro-inflammatory mediators in vaginal fluid and short cervical length in pregnancy.

Bratislavske lekarske listy·2020
Same author

Accounting for the impact of conservation on human well-being.

Conservation biology : the journal of the Society for Conservation Biology·2014
Same author

The wart lady of Kansas.

Journal of the Royal Society of Medicine·2010
Same author

Impaired iron transport activity of ferroportin 1 in hereditary iron overload.

The Journal of membrane biology·2006
Same author

Telomerase and human papillomavirus as diagnostic adjuncts for cervical dysplasia and carcinoma.

Human pathology·2004
Same author

Molecular evidence for the role of a ferric reductase in iron transport.

Biochemical Society transactions·2002

Area of Science:

  • Obstetrics and Gynecology
  • Neonatal Medicine
  • Public Health

Background:

  • Preterm birth is a significant cause of neonatal mortality and morbidity.
  • Reproductive tract infections are linked to preterm birth.
  • Current treatment strategies for preterm birth complications require optimization.

Purpose of the Study:

  • To evaluate the cost-effectiveness of preventing preterm birth related to reproductive tract infections.
  • To assess the benefits of adjunctive antibiotic treatment in mothers with preterm birth complications.
  • To provide evidence-based recommendations for providers and payers.

Main Methods:

  • Meta-analyses of studies on adjunctive antibiotic treatment for preterm premature rupture of membranes.
  • Analysis of treatment regimens for preterm labor, including single-agent therapies.
  • Economic evaluation of preterm birth prevention strategies.

Main Results:

  • Adjunctive antibiotic treatment shows clear neonatal and maternal benefits in preterm premature rupture of membranes.
  • Single-agent antibiotic regimens (erythromycin, clindamycin) are effective for preterm labor, covering Group B Streptococcus.
  • Effective prevention and treatment of preterm birth offer substantial cost savings.

Conclusions:

  • Evidence supports the use of specific antibiotic regimens to prevent preterm birth and its complications.
  • Implementing these evidence-based strategies presents cost-saving opportunities for healthcare systems.
  • Preventing preterm birth significantly improves child survival and reduces long-term impairment.

Related Experiment Videos