Related Experiment Video
Updated: Sep 3, 2026

Ferric Chloride-induced Murine Thrombosis Models
Published on: September 5, 2016
Modulating platelet function with selective thrombin inhibitors
1Center for Molecular and Vascular Biology, University of Leuven, Belgium.
Abstract:
In addition to its pivotal role in blood coagulation, thrombin is one of the most important agonists for platelet recruitment and aggregation. Thrombin inhibitors impede thrombin-induced platelet aggregation but have no effect on aggregation induced by other agonists. A review is presented of selective thrombin inhibitors now in clinical investigation, some of which are also orally active.
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