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Published on: May 29, 2020
Detecting GD and preeclampsia. Effectiveness of routine urine screening for glucose and protein
1Department of Obstetrics and Gynecology, Morehouse College, School of Medicine, Atlanta, Georgia, USA.
Insights
Routine urinalysis for proteinuria and glycosuria in pregnancy is not effective. Oral glucose screening and blood pressure monitoring are better for detecting gestational diabetes and preeclampsia, reducing patient and clinic burden.
Area of Science:
- Obstetrics and Gynecology
- Clinical Chemistry
- Maternal-Fetal Medicine
Background:
- Routine antepartum urinalysis for proteinuria and glycosuria is a common practice in prenatal clinics.
- The clinical utility and necessity of this routine screening method warrant re-evaluation.
Purpose of the Study:
- To assess the effectiveness of routine urine analysis for proteinuria and glycosuria during antepartum visits.
- To determine if alternative screening methods are more efficient for detecting gestational diabetes and preeclampsia.
Main Methods:
- Retrospective review of 610 antepartum medical records.
- Analysis of proteinuria and glycosuria findings in relation to preeclampsia and gestational diabetes diagnoses.
Main Results:
- Proteinuria was detected in 18% of patients; 2.8% developed preeclampsia.
- Glycosuria was present in 2.5% of patients; 1.7% had gestational diabetes.
- Proteinuria preceded hypertension in 17.7% of preeclampsia cases; glycosuria was present in 36% of gestational diabetes cases.
Conclusions:
- Oral 50-g glucose screening and blood pressure monitoring are superior screening methods for gestational diabetes and preeclampsia.
- Eliminating routine urinalysis can reduce patient inconvenience and clinic staffing requirements.
Objective:
To assess why urine collection and analysis for proteinuria and glycosuria is routinely performed during each antepartum visit at prenatal clinics.
Study Design:
Six hundred ten antepartum medical records were reviewed.
Results:
One hundred nine (18%) patients had proteinuria, while 17 patients (2.8%) developed preeclampsia. Fifteen patients (2.5%) had at least one episode of glycosuria (100 mg/dL), while 11 had gestational diabetes. Of those with gestational diabetes, four (36%) had glycosuria. Of those with preeclampsia, three (17.7%) had proteinuria that preceded the finding of hypertension.
Conclusion:
These results support our observation that routine oral 50-g glucose diabetes screening and careful monitoring of blood pressure are better screens for gestational diabetes and preeclampsia. The increased patient inconvenience and clinic staffing necessary for routine urinalysis may be avoided by eliminating that ritual.
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