Related Experiment Video
Updated: Aug 7, 2026

Teratoma Generation in the Testis Capsule
Published on: November 7, 2011
Testosterone-producing benign cystic teratoma with virilism. A case report
M W Tomlinson1, A A Alaverdian, V Alaverdian
1Department of Obstetrics and Gynecology, Grace Hospital/Wayne State University, Detroit, Michigan 48325, USA.
Background:
Mature cystic teratomas are common tumors in reproductive-age women. Biologic activity in a small percentage of these neoplasms is well recognized. Thyroid hormone is the most commonly secreted substance.
Case:
A 25-year-old woman presented with a large abdominal mass and virilism. Preoperative evaluation revealed elevated creatinine and testosterone levels and anemia. Computed tomography (CT) showed fat-fluid levels and multiple calcifications within the mass and obstruction of the right kidney. At surgery a 30-cm left ovarian mass was removed. Left ovarian vein testosterone levels were markedly elevated. Pathology reported a mature cystic teratoma. Postoperatively the testosterone levels returned to normal.
Conclusion:
In rare instances androgen production and virilization may occur with mature cystic teratoma.
Related Concept Videos
Spermatogenesis
Teratogenicity
Testes: Gross Anatomy
Each testis is surrounded by the tunica albuginea, a dense connective tissue layer that provides structural support and protection. This layer is covered by an outer serous membrane called the tunica vaginalis, which helps reduce friction...
Infertility in Males
Disorders of the Male Reproductive System
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Cirrhosis I: Introduction

