In vitro susceptibility of goat mononuclear cells to bluetongue virus

Goat peripheral blood mononuclear cells were cultured and their susceptibility to bluetongue virus (BTV) serotype 1 was tested. A small number of adherent and non-adherent cells were found positive for BTV antigens by immunoperoxidase and immunofluorescence tests. Both adherent and non-adherent cells supported limited level of viral replication as evidenced by low titre in the biological assay, thus indicating their susceptibility.