Further evidence for the specific involvement of the flocculus in the vertical vestibulo-ocular reflex (VOR)

We examined the simple-spike activity of floccular Purkinje (P) cells during sinusoidal pitch rotation and vertical optokinetic stimuli in alert, head-fixed cats. The great majority of pitch-responding P cells also responded to optokinetic stimuli with increased activity when the directions of the resultant eye movements were the same. During rapid modification of the VOR induced by visual pattern movement, modulation amplitudes of the cells tested increased together with the eye velocity increase. Maximal activation directions of these cells studied during vertical rotation in many planes were near the vertical canal planes. These results suggest that the activity of the majority of pitch-responding P cells contains a vertical eye velocity component during vestibular or optokinetic stimuli in addition to canal inputs during pitch rotation.