Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Primary spinal column sarcomas

E Tasdemiroglu1, E Bagatur, I Ayan

  • 1Incirli Hospital, Neurosurgery Service, Istanbul, Turkey.

Acta Neurochirurgica
|January 1, 1996
PubMed
Summary

Primary spinal column sarcomas in children, including Ewing

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prognostic factors associated with the response to sunitinib in patients with metastatic renal cell carcinoma.

Current oncology (Toronto, Ont.)·2013
Same author

Spontaneous pneumothorax in children with osteosarcoma: report of three cases and review of the literature.

Acta chirurgica Belgica·2012
Same author

De novo germline mutations of the p53 gene in young children with sarcomas.

Oncology reports·2011
Same author

Effect of field placement errors on dose at junction between divergence matching and half-beam block techniques in craniospinal irradiation.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology·2007
Same author

Human immunodeficiency virus-negative tonsil Kaposi's sarcoma and Hodgkin's disease: case report and review of the literature.

Journal of B.U.ON. : official journal of the Balkan Union of Oncology·2007
Same author

Diagnosis and management of brain metastases.

Hematology/oncology clinics of North America·2002

Area of Science:

  • Pediatric Oncology
  • Orthopedic Oncology
  • Spinal Surgery

Background:

  • Primary spinal column sarcomas are rare in pediatric patients.
  • These tumors can present with significant neurological deficits and pain.
  • Early diagnosis and multidisciplinary treatment are crucial for outcomes.

Purpose of the Study:

  • To present five cases of primary spinal column sarcomas in children.
  • To analyze the clinical presentation, treatment, and outcomes of these rare tumors.
  • To evaluate the role of surgical decompression and stabilization in managing spinal sarcomas.

Main Methods:

  • Retrospective review of five pediatric cases with primary spinal column sarcomas.
  • Treatment included chemotherapy, radiotherapy, subtotal tumor resection, and spinal decompression.
  • Surgical interventions focused on decompression, stabilization, and cytoreduction.

Main Results:

  • Five pediatric patients (ages 1-14) with Ewing's sarcoma, mesenchymal chondrosarcoma, and osteogenic sarcoma were treated.
  • All patients presented with pain and progressive weakness.
  • Three patients survived 10-98 months post-diagnosis, with one in complete remission.

Conclusions:

  • Primary spinal column sarcomas in children require a combined treatment approach.
  • Surgical decompression and stabilization are vital for neurological improvement and quality of life.
  • Multimodal therapy including chemotherapy, radiotherapy, and surgery offers potential for long-term survival.

Related Experiment Videos