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Expression of the PIP/GCDFP-15 gene and survival in breast cancer
1Department of Pathology, University of Western Australia, Queen Elizabeth II Medical Centre, Nedland, Australia.
Virchows Archiv : an International Journal of Pathology
|December 1, 1996
Abstract:
Expression of the PIP/GCDFP-15 gene was determined by measuring PIP/GCDFP-15-mRNA in breast carcinomas of 91 patients. The patients were followed-up for an average of 47 months after initial diagnosis and treatment of the disease. There were no deaths in the group of 14 patients with tumours of high PIP/GCDFP-15-mRNA levels, while 16 of 77 patients of the group with low PIP/GCDFP-15-mRNA tumour levels died. A similar advantage for high PIP/GCDFP-mRNA expression was observed with regard to disease free survival.