[The body's antioxidative systems in bronchopulmonary disease]

A comprehensive study was made of the parameters of antioxidative defense in patients with chronic nonspecific pulmonary diseases (CNSPD), malignant and benign respiratory tumors. The highest deficiency of antioxidants both in blood and lung tissues were noted in CNSPD patients. With malignant tumors, the level of radical inhibitors depends on the stage of malignancy and the histological pattern of a tumor. There were correlations between the studied parameters in the blood and cytoplasmic fraction of lung tissue in cancer patients. It is suggested that redistribution of antioxidative resources occurs in the body in adenocarcinoma and small-cell carcinoma.