Scintigraphic measurement of gastric emptying and ultrasonographic assessment of antral area: relation to appetite
- K Hveem 1, K L Jones , B E Chatterton , M Horowitz
- 1Department of Medicine, Royal Adelaide Hospital, South Australia.
- 0Department of Medicine, Royal Adelaide Hospital, South Australia.
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View abstract on PubMed
Summary
This summary is machine-generated.Ultrasound accurately measures gastric emptying, correlating with fullness. This non-invasive method shows comparable sensitivity to scintigraphy for liquid nutrient emptying.
Area Of Science
- Gastroenterology
- Medical Imaging
- Physiology
Background
- Ultrasound offers potential advantages over scintigraphy for gastric emptying measurement.
- Limited data exists on the accuracy of ultrasound for gastric emptying assessment.
Purpose Of The Study
- To evaluate the relationship between ultrasonographic antral area measurements and scintigraphic gastric emptying.
- To assess the correlation between ultrasound measurements and postprandial satiation.
Main Methods
- Seven healthy volunteers participated in the study.
- Subjects consumed dextrose-water or beef soup labeled with technetium-99m sulphur colloid.
- Gastric emptying was measured using both scintigraphy and ultrasound.
Main Results
- Ultrasound and scintigraphy showed comparable 50% emptying times (T50s) for both liquids.
- Strong correlations were observed between scintigraphic and ultrasound T50s.
- Postprandial fullness after dextrose correlated significantly with the postprandial increase in antral area measured by ultrasound.
Conclusions
- Ultrasound is a sensitive method for quantifying gastric emptying of low and high nutrient liquids, comparable to scintigraphy.
- Ultrasound measurements correlate with postprandial satiation.
- Antral distension, measured by ultrasound, may mediate postprandial satiation.
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