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[A tropical ulcer; cutaneous diphtheria]

B F Werdmuller1, M Brakman, R W Vreede

  • 1Diagnostisch Centrum SSDZ, afd. Medische Microbiologie, Delft.

Nederlands Tijdschrift Voor Geneeskunde
|November 30, 1996
PubMed
Summary

Cutaneous diphtheria, a bacterial skin infection caused by Corynebacterium diphtheriae, can manifest as foot ulcers following insect bites. Prompt antibiotic treatment ensures full recovery, highlighting the importance of recognizing this condition.

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Area of Science:

  • Infectious Diseases
  • Dermatology
  • Microbiology

Background:

  • Cutaneous diphtheria is a bacterial infection caused by Corynebacterium diphtheriae.
  • It is characterized by skin lesions, often with a grey pseudomembrane.
  • The infection can occur in travelers returning from endemic areas.

Observation:

  • A 43-year-old woman developed non-healing foot ulcers after insect bites during travel to Gambia and Senegal.
  • The ulcers were diagnosed as cutaneous diphtheria.
  • A characteristic grey pseudomembrane was noted on the ulcer.

Findings:

  • The patient was successfully treated with antibiotics.
  • Corynebacterium diphtheriae was identified as the causative agent.
  • The patient experienced a full recovery.

Implications:

  • Early diagnosis and antibiotic treatment are crucial for managing cutaneous diphtheria.
  • Recognition of the characteristic pseudomembrane aids in diagnosis.
  • Toxin testing and antitoxin therapy may be necessary for toxigenic strains.
  • Screening of social contacts can be advised in certain cases.

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