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Updated: Jul 25, 2026
05:05
Ultrasound Cyclo Plasty in Eyes with Glaucoma
Published on: January 26, 2018
Histopathologic observations on human eyes following cyclocryotherapy for glaucoma
Transactions. Section on Ophthalmology. American Academy of Ophthalmology and Otolaryngology
|January 1, 1977
Summary
Cyclocryotherapy effectively destroys human ciliary epithelium, causing permanent damage. Other factors, not cell regrowth, explain treatment failures for intraocular pressure control.
Area of Science:
- Ophthalmology
- Pathology
- Cryosurgery
Background:
- Clinicopathologic study of 12 human eyes treated with cyclocryotherapy.
- Analysis of technical factors and interval from treatment to enucleation (12 days to 4.5 years).
Observation:
- Pathologic examination revealed permanent, massive destruction and scarring of ciliary body epithelium in all cases.
- Pigment epithelium showed higher susceptibility to cryosurgical damage than non-pigment epithelium.
- Ciliary body stroma/muscle scarring (11 patients), scleral damage (9 patients), and fibrous membrane lining (5 patients) were observed.
Findings:
- Cyclocryotherapy induces permanent destruction of human ciliary epithelium.
- Pigment epithelium is more vulnerable to cryosurgical injury.
Implications:
- The study confirms cyclocryotherapy's efficacy in ciliary epithelium destruction.
- Treatment failure in controlling intraocular pressure is attributed to factors beyond epithelial cell regrowth.
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