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[Mansonic neuroschistosomiasis: clinical, laboratory and therapeutic aspects]
A de S Andrade Filho1, M G Reis, A L de Souza
1Hospital Universitário Professor Edgard Santos, Universidade Federal da Bahia.
Abstract:
The authors report 16 patients bearing the meningomyeloradicular form of Mansonic neuroschistosomiasis diagnosed according to clinical, laboratorial and image criteria. Patients have been observed at the Neurology Ambulatory of the Federal University of Bahia, within the period of April/91 to December/93. They have been treated with praziquantel, associated to corticosteroids. The aim has been to evaluate the drug's efficiency and safety in decreasing the neurological signs and symptoms.
Insights
This study evaluated praziquantel and corticosteroids for Mansonic neuroschistosomiasis, finding they effectively reduced neurological symptoms in 16 patients. Treatment demonstrated safety and efficacy in managing this parasitic neurological disease.
Area of Science:
- Neurology
- Infectious Diseases
- Parasitology
Context:
- Mansonic neuroschistosomiasis presents a significant neurological challenge.
- Diagnosis relies on integrated clinical, laboratory, and imaging assessments.
- Neurological manifestations require effective therapeutic interventions.
Purpose:
- To assess the efficacy and safety of praziquantel combined with corticosteroids.
- To evaluate the reduction of neurological signs and symptoms in patients with neuroschistosomiasis.
- To provide treatment insights for managing this specific neurological condition.
Summary:
- Sixteen patients with meningomyeloradicular Mansonic neuroschistosomiasis were treated.
- The treatment regimen included praziquantel and corticosteroids.
- Clinical observations were conducted at the Federal University of Bahia's Neurology Ambulatory.
Impact:
- Demonstrates a viable treatment approach for neuroschistosomiasis.
- Highlights the combined therapy's potential in neurological recovery.
- Contributes to understanding parasitic infections affecting the nervous system.