Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Reduced stereoacuity in Williams syndrome

L S Sadler1, S E Olitsky, J D Reynolds

  • 1Department of Pediatrics, State University of New York at Buffalo, Children's Hospital, NY 14222, USA.

American Journal of Medical Genetics
|December 18, 1996
PubMed
Summary

Strabismus and reduced stereoacuity are common in Williams syndrome (WS). This study suggests these vision issues may stem from abnormal brain development in the occipitoparietal cortex.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recent declines in salmon body size impact ecosystems and fisheries.

Nature communications·2020
Same author

Integration of low loss vertical slot waveguides on SOI photonic platforms for high efficiency carrier accumulation modulators.

Optics express·2020
Same author

Peripheral tissue oxygenation and the number of organs transplanted per donor.

Anaesthesia and intensive care·2018
Same author

The effect of inhalational anaesthesia during deceased donor organ procurement on post-transplantation graft survival.

Anaesthesia and intensive care·2018
Same author

Reduced growth in wild juvenile sockeye salmon Oncorhynchus nerka infected with sea lice.

Journal of fish biology·2017
Same author

Improving fast atom bombardment mass spectra: The influence of some controllable parameters on spectral quality.

Journal of the American Society for Mass Spectrometry·2013

Area of Science:

  • Ophthalmology
  • Neuroscience
  • Genetics

Background:

  • Strabismus is a known manifestation of Williams syndrome.
  • Williams syndrome is a genetic disorder affecting development.

Purpose of the Study:

  • To evaluate ophthalmologic function in patients with Williams syndrome.
  • To emphasize binocularity and stereoacuity in the assessment.

Main Methods:

  • Ophthalmologic examination of 12 patients with Williams syndrome.
  • Assessment of binocular vision and stereoacuity.

Main Results:

  • Four out of 12 patients (33%) presented with measurable strabismus.
  • Six of the remaining eight patients showed reduced stereoacuity.
  • Subnormal binocular vision was observed in a significant portion of the cohort.

Conclusions:

  • Williams syndrome patients frequently exhibit strabismus and impaired binocular vision.
  • Reduced stereoacuity and visuospatial deficits may be linked to occipitoparietal cortex abnormalities in WS.
  • Further research into brain morphogenesis is warranted to understand visual impairments in Williams syndrome.

Related Experiment Videos