Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Serum ferritin: does it differ from tissue ferritin?

M C Linder1, K J Schaffer, M Hazegh-Azam

  • 1Department of Chemistry and Biochemistry, California State University, Fullerton 91623, USA.

Journal of Gastroenterology and Hepatology
|November 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Building CAR-E: A Novel Artificial Intelligence Agent for Coaching Conversations.

Perspectives on medical education·2026
Same author

[Comparison of the efficacy and safety of 36 000 IU vs. 40 000 IU recombinant human erythropoietin for the treatment of cancer-related anemia: a multicenter, open-label, randomized controlled trial].

Zhonghua zhong liu za zhi [Chinese journal of oncology]·2026
Same author

Diverse Properties of Electron Forbush Decreases Revealed by the Dark Matter Particle Explorer.

Physical review letters·2026
Same author

[Characteristics of peak expiratory flow and analysis of risk factors for its decline in stroke patients].

Zhonghua yi xue za zhi·2026
Same author

[Advancements in understanding the pathogenesis of thoracic aortic aneurysm].

Zhonghua xin xue guan bing za zhi·2024
Same author

[One case of myocardial damage caused by carbamate pesticide poisoning].

Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases·2023
Same journal

Patient-Level Predictors of Procedural Success in Colon Capsule Endoscopy: A Systematic Review and Meta-Analysis.

Journal of gastroenterology and hepatology·2026
Same journal

Preventive Effect of Helicobacter pylori Treatment on Colorectal Cancer Incidence and Mortality.

Journal of gastroenterology and hepatology·2026
Same journal

Toward the Era of Precision Immunotherapy: The Clinical Landscape and Future Directions of mRNA Vaccines for the Treatment of Hepatocellular Carcinoma.

Journal of gastroenterology and hepatology·2026
Same journal

From Chronic Atrophic Gastritis to Low-Grade Intraepithelial Neoplasia: A Proteomic Study on the Sequential Progression of Gastric Precancerous Lesions.

Journal of gastroenterology and hepatology·2026
Same journal

Resource-Stratified Carbon-Adjusted Quality Indicators for Green Endoscopy.

Journal of gastroenterology and hepatology·2026
Same journal

Five-Year Outcomes and Disease Trajectories in Moderate-to-Severe Ulcerative Colitis: A Korean Multicenter Inception Cohort.

Journal of gastroenterology and hepatology·2026
See all related articles

Horse serum ferritin differs structurally from spleen ferritin in molecular weight, iron, and amino acid sequence. Initial characterization of serum ferritin subunits is also presented.

Area of Science:

  • Biochemistry
  • Comparative protein analysis

Background:

  • Ferritin is a protein complex that stores iron.
  • Serum ferritin and spleen ferritin are distinct isoforms with different physiological roles.
  • Understanding structural differences is key to elucidating functional variations.

Purpose of the Study:

  • To structurally compare horse serum ferritin with horse spleen ferritin.
  • To characterize the molecular and biochemical properties of horse serum ferritin.
  • To initiate the molecular cloning of horse serum ferritin subunits.

Main Methods:

  • Isolation and purification of serum and spleen ferritin from horse.
  • Comparative analysis of molecular weight, iron content, and carbohydrate composition.
  • Subunit size determination using SDS-PAGE.

Related Experiment Videos

  • Amino acid sequence comparison.
  • Molecular cloning of ferritin subunit fragments.

    • Main Results:

    • Horse serum ferritin exhibited significant differences from spleen ferritin in molecular weight, iron content, carbohydrate composition, and subunit size.
    • Amino acid sequence analysis revealed marked distinctions between the two ferritin types.
    • Initial molecular cloning efforts yielded candidate clones for fragments of two serum ferritin subunits.

    Conclusions:

    • Horse serum ferritin is structurally distinct from horse spleen ferritin.
    • These structural variations likely contribute to their different biological functions.
    • Further molecular characterization of serum ferritin subunits is warranted.