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Multi-fractionated stereotactic radiotherapy

T L Edlund1, J H Moeller, D D Leavitt

  • 1University of Utah Health Science Center, Salt Lake City 84132, USA.

Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists
|January 1, 1996
PubMed
Summary
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This study introduces a new multi-fractionated stereotactic radiotherapy technique, extending the precision of stereotactic radiosurgery to fractionated treatments for brain conditions. It ensures accurate patient positioning without invasive skull fixation, enhancing treatment delivery.

Area of Science:

  • Medical Physics
  • Radiation Oncology
  • Neurosurgery

Background:

  • Stereotactic radiosurgery (SRS) offers precision for arteriovenous malformations and brain metastases.
  • Fractionated radiotherapy is crucial for pituitary tumors and brain boost fields.
  • Bridging the precision gap between SRS and fractionated radiotherapy is essential.

Purpose of the Study:

  • To develop a multi-fractionated stereotactic radiotherapy technique.
  • To adapt SRS precision for fractionated treatments.
  • To enable reproducible patient immobilization without invasive fixation.

Main Methods:

  • Utilized SRS experience as a model for technique development.
  • Integrated existing devices: Brown-Roberts-Wells (BRW) localizer and CT localizer.

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  • Employed non-coplanar shaped field treatment planning.
  • Developed non-invasive immobilization using polyurethane foam and heat-moldable plastics.

    • Main Results:

    • Successfully developed a multi-fractionated stereotactic radiotherapy technique.
    • Achieved reproducible patient positioning through advanced immobilization.
    • Demonstrated feasibility of daily immobilization without skull fixation.
    • Established a method to implement SRS-level precision in fractionated radiotherapy.

    Conclusions:

    • The new technique successfully extends SRS precision to fractionated radiotherapy.
    • Non-invasive immobilization techniques ensure reproducible patient positioning.
    • This advancement improves treatment accuracy for various brain conditions requiring fractionated radiation therapy.