Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Improved dose distribution in the brain by collimator rotation

H T Kohut1, J Krishnamoorthy, V King

  • 1Department of Radiation Oncology, Albany Medical College, NY 12208, USA.

Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists
|January 1, 1996
PubMed
Summary

Standard wedges can improve radiation dose distribution for partial brain treatments. Rotating the collimator 45 degrees with a superior-lateral wedge placement minimizes over- and under-dosage in the planning target volume.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The influence of initial spinal cord haematoma and cord compression on neurological grade improvement in acute traumatic spinal cord injury: A prospective observational study.

Journal of the neurological sciences·2022
Same author

Oral vaccination of dogs with a monovalent live-avirulent vaccine confers 1 year of immunity against Bordetella bronchiseptica challenge.

Veterinary journal (London, England : 1997)·2021
Same author

Tantalum trabecular metal implants in anterior cervical corpectomy and fusion: 2-year prospective analysis.

Journal of clinical neuroscience : official journal of the Neurosurgical Society of Australasia·2016
Same author

HYSTEROSALPINGOGRAPHY AND LAPAROSCOPY IN EVALUATING FALLOPIAN TUBES IN THE MANAGEMENT OF INFERTILITY IN COTONOU, BENIN REPUBLIC.

Journal of the West African College of Surgeons·2015
Same author

Use of an anti-GnRF vaccine to suppress estrus in crossbred Iberian female pigs.

Theriogenology·2015
Same author

In response to letter to the editor (Regina Hofmann-Lehmann, Laura S. Levy and Brian Willett)--Comparing the efficacy of FeLV vaccines.

Vaccine·2015

Area of Science:

  • Radiation Oncology
  • Medical Physics
  • Radiotherapy

Background:

  • The complex curvature of the human skull presents challenges in delivering uniform radiation doses to the brain.
  • Standard radiation therapy techniques often use wedges to compensate for skull curvature, but this can lead to uneven dose distribution.
  • Three-dimensional compensators offer precise dose shaping but are costly and complex to fabricate, limiting their widespread use.

Purpose of the Study:

  • To investigate a cost-effective method for improving dose distribution in partial brain radiotherapy.
  • To evaluate the efficacy of a modified standard wedge technique in compensating for cranial curvature.

Main Methods:

  • A standard wedge was used in conjunction with a 45-degree collimator rotation.
  • The wedge was positioned with its heel in a superior-lateral orientation.

Related Experiment Videos

  • Dose distribution within the planning target volume was analyzed.

    • Main Results:

    • The modified standard wedge technique significantly improved dose distribution compared to standard wedge placement.
    • This method effectively reduced areas of over- and under-dosage within the planning target volume.
    • The technique offers a practical solution for optimizing radiation delivery in partial brain treatments.

    Conclusions:

    • Rotating the collimator 45 degrees and using a superior-lateral wedge placement is an effective strategy to improve dose distribution in partial brain radiotherapy.
    • This approach provides a more accessible alternative to complex 3D compensators for managing cranial curvature in radiation planning.