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Updated: Aug 10, 2026
Murine Model of Controlled Cortical Impact for the Induction of Traumatic Brain Injury
Published on: August 16, 2019
Severe head injuries: an outcome prediction and survival analysis
Objective:
To identify the predictors determined early after admission and associated with unfavorable outcome or early (within 48 h) death after severe head injury.
Design:
Prospective cohort study.
Setting:
A neurosurgical intensive care unit in a university hospital.
Patients:
198 consecutive comatose patients hospitalized from 1989 to 1992.
Results:
Logistic regression showed that a combination of age, best motor response score from the Glasgow Coma Scale, and hypoxia provided a good prediction model of unfavorable outcome (sensitivity = 0.93). The length of participation of survivors was 6 to 61 months (median 27.1). The Cox model demonstrated age, motor score less than 3, mydriasis, and hypoxia as poor prognosis factors.
Conclusions:
Clinicians can determine the odds of a good outcome from the combination of three easily measurable factors using a simple diagram constructed from logistic regression. Survival analysis showed that motor score adjusted values greater than 3 had the same prognosis.
