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Further defining the risks confronting twins

W F Powers1, N S Wampler

  • 1Joint Program in Neonatology, Harvard Medical School, Boston, Massachusetts, USA.

American Journal of Obstetrics and Gynecology
|December 1, 1996
PubMed
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Twin pregnancy risks for infant death and low birth weight are higher for Black infants, male-male pairs, and younger mothers. These factors significantly influence adverse outcomes in twin births.

Area of Science:

  • Perinatal epidemiology
  • Maternal-fetal medicine
  • Reproductive health

Background:

  • Twin pregnancies carry inherently higher risks than singleton gestations.
  • Understanding specific risk factors is crucial for optimizing perinatal care and outcomes.

Purpose of the Study:

  • To determine absolute and relative risks for adverse outcomes in twin pregnancies.
  • To stratify these risks by maternal race, maternal age, and twin gender pair combinations.

Main Methods:

  • Analysis of 138,779 twin pregnancies from U.S. Linked Birth/Infant Death Data Sets (1985-1988).
  • Observational cohort study examining neonatal and infant mortality, low birth weight, and preterm delivery (<33 and <35 weeks).

Main Results:

Related Experiment Videos

  • Increased risks observed for Black infants, male-male twin pairs, and younger mothers.
  • Relative risks for adverse outcomes were highest in male-male twins born to young Black mothers compared to older White mothers with male-female twins.

Conclusions:

  • Maternal race, maternal age, and twin gender composition significantly modify risks in twin pregnancies.
  • These findings are vital for accurate counseling of women with twin pregnancies.
  • Acknowledging baseline risk variations is essential for robust research on interventions in twin gestations.