Potential of neurotrophic factors in therapy of Parkinson's disease
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J C Möller1, J Sautter, A Kupsch
1Department of Neurology, University of Munich, Federal Republic of Germany.
Abstract:
Neurotrophic factors of dopaminergic neurons may represent a potential neuroprotective therapy for PD. This article reviews published experiments that demonstrate the effects of neurotrophic factors on dopaminergic neurons in vitro and in vivo. At present this issue is predominantly investigated in basic neuroscientific research. Its possible future clinical relevance is discussed.