New triterpenoid saponins from Gynostemma pentaphyllum
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High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC
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1Shanghai Institute of Materia Medica, Academia Sinica, People's Republic of China.
Journal of Natural Products
|December 1, 1996
Abstract:
Three new triterpenoidal saponins (1-3), together with the known compound 4, were isolated from a MeOH extract of the aerial parts of Gynostemma pentaphyllum. Their structures were elucidated on the basis of chemical and spectral methods, such as 1H-1H DQFCOSY, HMQC, HMBC, and TOCSY NMR spectra. The aglycon moiety of 1 and 2 is a new dammarane-type triterpene 12-oxo-2 alpha, 3 beta, 20 (S)-trihydroxydammar- 24-ene.