Jove
Visualize
Contact Us

Related Experiment Videos

Nasal dysplasia

R A de Blécourt1, R Roddi, J P Berg

  • 1Department of Plastic & Reconstructive Surgery, University Hospital Maastricht, The Netherlands.

Annals of Plastic Surgery
|December 1, 1996
PubMed
Summary

This case study details a rare congenital nasal malformation, unilateral left nostril duplication, classified as type IV nasal dysplasia. Surgical correction was successful, offering insights into managing this rare condition.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Improvement of Storage Medium for Cultured Human Retinal Pigment Epithelial Cells Using Factorial Design.

Scientific reports·2018
Same author

Serotonin transporter polymorphisms predict response inhibition in healthy volunteers.

Neuroscience letters·2014
Same author

Biochemical characterization of four novel mutations in the thyroid hormone receptor beta gene in patients with resistance to thyroid hormone.

Scandinavian journal of clinical and laboratory investigation·2009
Same author

Association between serum 25(OH)D and death from prostate cancer.

British journal of cancer·2009
Same author

Comparison of genetic risk in three candidate genes (TCF7L2, PPARG, KCNJ11) with traditional risk factors for type 2 diabetes in a population-based study--the HUNT study.

Scandinavian journal of clinical and laboratory investigation·2008
Same author

The relation between size at birth and risk of type 1 diabetes is not influenced by adjustment for the insulin gene (-23HphI) polymorphism or HLA-DQ genotype.

Diabetologia·2006
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Area of Science:

  • Otolaryngology
  • Pediatric Surgery
  • Clinical Genetics

Background:

  • Congenital nasal malformations are rare, presenting unique diagnostic and management challenges.
  • The CHARGE association is a complex genetic disorder with multisystemic manifestations.
  • Accurate classification of nasal anomalies is crucial for understanding pathogenesis and guiding treatment.

Observation:

  • A young male presented with unilateral duplication of the left nostril.
  • The malformation was classified as type IV nasal dysplasia based on van der Meulen's morphogenetic system.
  • Associated anomalies included features of the CHARGE association: coloboma, heart defects, choanal atresia, growth retardation, and genital/ear deformities.

Findings:

  • Surgical correction using an L-approach was performed for the nasal duplication.
  • The L-approach yielded a satisfactory cosmetic and functional outcome 1 year postoperatively.
  • This case highlights the phenotypic variability within nasal dysplasias and CHARGE association.

Implications:

  • This report contributes to the scarce literature on unilateral nasal duplication and type IV nasal dysplasia.
  • Successful surgical management underscores the importance of early intervention in congenital nasal anomalies.
  • Understanding the interplay of nasal malformations with syndromes like CHARGE is vital for comprehensive patient care.

Related Experiment Videos