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Alternatives to estrogen replacement therapy for preventing osteoporosis
S T Haines1, B Cáceres, L Yancey
1Department of Pharmacy Practice and Science, School of Pharmacy, University of Maryland at Baltimore, USA.
Journal of the American Pharmaceutical Association (Washington, D.C. : 1996)
|December 1, 1996
Summary
Osteoporosis affects older Americans, especially women, causing disability and death. Treatments like hormone therapy, bisphosphonates, and supplements can prevent fractures and slow disease progression.
Area of Science:
- Gerontology
- Bone Biology
- Pharmacology
Background:
- Osteoporosis is a significant health concern in older adults, leading to disability and mortality.
- Women face a higher risk of developing osteoporosis compared to men.
Purpose of the Study:
- To review current therapeutic strategies for managing osteoporosis.
- To highlight the role of pharmacological and nutritional interventions in preventing fractures.
Main Methods:
- Literature review of existing treatments for osteoporosis.
- Analysis of drug classes including sex hormones, bisphosphonates, calcitonin, and sodium fluoride.
- Evaluation of calcium and vitamin D supplementation efficacy.
Main Results:
- Pharmacological agents can effectively halt osteoporosis progression and reduce fracture risk.
- Calcium and vitamin D supplementation shows promise in preventing osteoporosis development in high-risk groups.
- These supplements are beneficial as adjunctive therapy with other osteoporosis treatments.
Conclusions:
- Effective medical and nutritional interventions exist to combat osteoporosis.
- Early intervention and comprehensive treatment plans are crucial for managing osteoporosis and improving patient outcomes.