Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

[Injury to ascending aorta by cross-clamp--histologic evaluation]

T Takano1, Y Fukaya, H Tsunemoto

  • 1Department of Surgery, Shinshu University, Matsumoto, Japan.

[Zasshi] [Journal]. Nihon Kyobu Geka Gakkai
|December 1, 1996
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Influence of concurrent and staggered dosing of semi-solid nutrients on the pharmacokinetics of orally administered carbamazepine in rats.

Die Pharmazie·2022
Same author

Images of angioscopy and intravascular ultrasound for dislodged Angio-Seal<sup>®</sup> VIP vascular closure device.

Cardiovascular intervention and therapeutics·2021
Same author

Tumor microenvironment in triple-negative breast cancer: the correlation of tumor-associated macrophages and tumor-infiltrating lymphocytes.

Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico·2021
Same author

SAPPHIRE: a randomised phase II study of planned discontinuation or continuous treatment of oxaliplatin after six cycles of modified FOLFOX6 plus panitumumab in patients with colorectal cancer.

European journal of cancer (Oxford, England : 1990)·2019
Same author

Efficient plantlet regeneration from protoplasts isolated from suspension cultures of poplar (Populus alba L.).

Plant cell reports·2019
Same author

Usefulness of ascites cytology for the evaluation of chemotherapy response in ovarian carcinosarcoma.

Cytopathology : official journal of the British Society for Clinical Cytology·2018

Vascular clamp trauma to the ascending aorta increases with higher occlusive intensity. Microscopic examination revealed severe damage at the proximal site due to significant clamp pressure.

Area of Science:

  • Cardiovascular Surgery
  • Vascular Biology
  • Histopathology

Context:

  • Aortic dissection necessitates surgical intervention, often involving aortic arch and ascending aorta replacement.
  • Cross-clamping the ascending aorta is a critical step during these procedures.
  • Understanding clamp-induced vessel trauma is crucial for optimizing surgical techniques.

Purpose:

  • To microscopically evaluate ascending aorta injury caused by vascular cross-clamping.
  • To correlate the degree of vessel wall trauma with the measured occlusive intensity of the clamp.

Summary:

  • Six patients undergoing aortic dissection repair had their ascending aorta segments analyzed post-resection.
  • Vessel segments were examined microscopically for trauma (Grade 1-3) and clamp intensity was measured.

Related Experiment Videos

  • Higher clamp pressure correlated with more severe histological changes, including intima disruption and endothelial cell loss.

    • Impact:

    • Findings demonstrate a direct relationship between vascular clamp pressure and ascending aorta injury.
    • This highlights the need for careful clamp management to minimize iatrogenic trauma during aortic surgery.
    • Results can inform the development of safer clamping strategies and improved patient outcomes.