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[Marchiafava-Bignami disease: development with flare-up]

O Moreaud¹, N Dufossé, J Pellat

¹Service de Neurologie et de Neuropsychologie, CHU, Grenoble.

Revue Neurologique

|August 1, 1996

Summary

Marchiafava-Bignami disease, a complication of chronic alcohol abuse, can lead to dementia. Even after initial recovery, repeated episodes may result in a poor long-term prognosis.

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Area of Science:

Neurology
Neuroscience
Toxicology

Background:

Marchiafava-Bignami disease (MBD) is a rare neurological complication associated with chronic ethanol intoxication.
MBD can present with diverse clinical courses, ranging from acute, fatal outcomes to progressive dementia or even favorable recoveries.
Acute worsening and partial recovery can occur during the course of chronic MBD.