Related Experiment Video
Updated: Aug 9, 2026

Two Methods of Heterokaryon Formation to Discover HCV Restriction Factors
Published on: July 16, 2012
[Hepatitis C virus. Structure and genetic variability]
1INSERM U.370, CHU Necker, Paris.
Abstract:
Infection by hepatitis C virus is characterized by a high rate of chronicity and low viremia. The virus has only been recently identified; it is a positively stranded RNA virus which shows homology in its genetic organisation with the Pestiviruses and Flaviviruses. There is not yet efficient culture system available. Several evidences indicate that the genetic variability of HCV genome might have important clinical implications; in particular infection by genotype 1b is less responsive to interferon treatment and, possibly, associated to more severe liver diseases.
Related Concept Videos
Viral Structure
Viral Mutations
Introduction to Virus
Size and Structure of Viral Genomes
Hepatitis
Viral Hepatitis I: Introduction

