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[Isolated congenital growth hormone deficiency. Severe hypoglycemia and neonatal giant cell hepatitis]
1Paediatrisk afdeling, Arhus Kommunehospital.
Ugeskrift for Laeger
|November 4, 1996
Abstract:
A case of congenital isolated growth hormone deficiency with neonatal giant cell hepatitis is described. Hypoplasia of the pituitary gland was detected by a MR-scan. Values of IGF-I, IGF-II, and IGF-BP-3 were low. Birth length and weight were normal; hypoglycaemia, jaundice, and failure to thrive were the most pronounced symptoms and present from the first day. Substitution therapy with growth hormone induced a remission of all symptoms. Growth was normal at follow-up at the age of two and a half years.