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Updated: Aug 18, 2026

Creation of Abdominal Adhesions in Mice
Published on: August 27, 2016
[Incidence distribution of postoperative adhesions after using different coagulation techniques. An animal experiment
1Abteilung Frauenheilkunde, Christian-Albrechts-Universität Kiel.
Abstract:
This study compares the incidence of adhesions after using the Endocoagulator by Semm with the incidence of adhesions after using the Nd-YAG-laser with 30 watts and 100 watts. At a total of 100 female Wistar-rats both, the uterine-horns and 2 correspondent spots at the ventral abdominal-walls were coagulatet. resp. vaporized. After 14 resp. 28 days a relaparotomie was made: 1. With the Nd-YAG-laser (30 and 100 watts) (significant) adhesions were found, at the uterine-horns in 100% of all cases with the Endokoagulator in 50%. At the peritoneal spots with the Nd-YAG-laser (30 and 100 watts) (not significant) adhesions were found in 10% of all cases, with the Endokoagulator 5% were found. 2. In addition to the macroscopic results histologic researches were also made: It was shown, that the treatment with Nd-YAG-laser develops a high grade of carbonisation-waste, which is known to be a main cause for the development of adhesions. 3. The division in 14- and 28-day-groups showed no significant differences in the incidence of adhesions. 4. There were found more significant adhesions at the uterine-horns than at the peritoneal-spots.

