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A linkage analysis in two families with bilateral retinoblastoma
1Department of Medical Biology, Hacettepe University Faculty of Medicine, Ankara.
The Turkish Journal of Pediatrics
|October 1, 1996
Abstract:
Using polymerase chain reaction (PCR) amplification from blood samples, Xbal and BamHI polymorphisms were analyzed in two families with bilateral retinoblastoma. In one of the families it was predicted using the BamHI polymorphism that the 200 bp allele co-segregates with the disease. This family was uninformative for Xbal polymorphism. The second family was uninformative for both Xbal and BamHI polymorphism.