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Updated: Aug 15, 2026

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Published on: June 18, 2020
Prevention of recurrent esophageal bleeding and survival in patients with alcoholic cirrhosis: a randomized study
M Urbistondo1, E A Torres, F Castro
1Department of Medicine, University of Puerto Rico School of Medicine.
Objectives:
To compare endoscopic sclerotherapy, propranolol and distal splenorenal shunt in the prevention of rebleeding esophageal varices and mortality in alcoholic cirrhotics.
Methods:
Forty-three alcoholic cirrhotics that had bled from esophageal varices were randomized to sclerotherapy (13), shunt (15) or propranolol(15). Outcomes measured were rebleeding from varices and death.
Results:
There was no significant difference between the three treatment groups in relation to rebleeding rate or death. Continued alcohol consumption did not influence outcome.
Conclusions:
All three therapies were equally effective in preventing rebleeding from varices.
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