Interventional and surgical treatment of pancreatic abscess
K Mithöfer1, P R Mueller, A L Warshaw
1Department of Surgery, Massachusetts General Hospital, Harvard Medical School, 15 Parkman Street, WAC 336, Boston, Massachusetts 02114, USA.
Abstract:
Pancreatic abscess is one of the infectious complications of acute pancreatitis. It is a collection principally containing pus, but it may also contain variable amounts of semisolid necrotic debris. Most of these abscesses evolve from the progressive liquefaction of necrotic pancreatic and peripancreatic tissues, but some arise from infection of peripancreatic fluid or collections elsewhere in the peritoneal cavity. Included also are abscesses found after surgical débridement and drainage of pancreatic necrosis. Although open surgical treatment of infected necrosis is the established treatment of choice, percutaneous drainage of abscesses is successful in some circumstances. We used percutaneous catheter drainage in 39 patients during 1987-1995. Only 9 of 29 (31%) attempts at primary therapy were successful; 2 patients died, and 18 required subsequent surgical drainage. On the other hand, 14 of 14 patients with recurrent or residual abscesses after surgical drainage were successfully drained percutaneously. Percutaneous catheter drainage of pancreatic abscesses may be useful for initial stabilization of septic patients, drainage of further abscesses after surgical intervention (especially when access for reoperation will be difficult), associated abscesses remote from the pancreas, and selected unilocular collections at a sufficient interval after necrotizing pancreatitis to have allowed essentially complete liquefaction.
Insights
Percutaneous catheter drainage can effectively treat recurrent pancreatic abscesses after surgery. While primary percutaneous drainage of pancreatic abscesses has limited success, it is valuable for stabilizing septic patients and managing complex cases.
Area of Science:
- Gastroenterology
- Interventional Radiology
- Infectious Diseases
Background:
- Pancreatic abscess is a severe infectious complication of acute pancreatitis.
- Abscesses form from liquefied necrotic pancreatic/peripancreatic tissue or infected fluid collections.
- Open surgical treatment is standard, but percutaneous drainage is explored.
Purpose of the Study:
- To evaluate the efficacy of percutaneous catheter drainage for pancreatic abscesses.
- To assess its role in primary treatment versus management of post-surgical collections.
Main Methods:
- Retrospective analysis of 39 patients treated with percutaneous catheter drainage between 1987-1995.
- Categorization of patients into primary therapy attempts and those with recurrent/residual abscesses post-surgery.
Main Results:
- Primary percutaneous drainage success rate was 31% (9/29), with 2 deaths and 18 requiring surgery.
- Percutaneous drainage was successful in 100% (14/14) of patients with recurrent/residual abscesses post-surgery.
Conclusions:
- Percutaneous drainage is highly effective for recurrent/residual pancreatic abscesses after surgery.
- It serves as a useful adjunct for septic patient stabilization and managing complex/remote abscesses.
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