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Detection of HLA-DR associated with monocytotropic, primary, and plasma isolates of human immunodeficiency virus type
M N Saarloos1, B L Sullivan, M A Czerniewski
1Department of Immunology and Microbiology, Rush Presbyterian St. Luke's Medical Center, Chicago, Illinois 60612, USA.
Journal of Virology
|February 1, 1997
Abstract:
This study determined whether HLA-DR was incorporated into human immunodeficiency virus type 1 produced in vivo or by primary cultured cells. HLA-DR was associated with virions from primary isolates, macrophage cultures, and blood plasma. These results represent the first demonstration of major histocompatibility complex molecules associated with an in vivo source of virus.