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Incomplete brain infarction of reperfused cortex may be quantitated with iomazenil

J Nakagawara1, B Sperling, N A Lassen

  • 1Department of Neurosurgery and Nuclear Medicine, Nakamura Memorial Hospital, Sapporo, Japan.

Stroke
|January 1, 1997
PubMed
Summary

[123I]Iomazenil binding quantifies neuronal viability in stroke patients. This radioligand helps assess salvaged brain tissue after reperfusion, indicating the extent of incomplete infarction.

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2026-06-19T13:49:54.016914+00:00

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Ischemic Stroke ll: Pathophysiology01:15

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An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...

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