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Foot problems in the diabetic transplant recipient

A J Kalker¹, J D Pirsch, D Heisey

¹Department of Surgery, University of Wisconsin Hospital & Clinics, Madison 53705, USA.

Clinical Transplantation

|December 1, 1996

Summary

This summary is machine-generated.

Diabetic transplant patients face high risks of foot problems and amputation. Maintaining good circulation and sensation, and avoiding smoking, significantly reduce amputation risk.

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Area of Science:

Nephrology
Transplantation
Diabetology

Background:

Diabetic patients undergoing organ transplantation are at elevated risk for lower extremity complications.
Foot pathology in this population can lead to severe outcomes, including amputation.

Purpose of the Study:

To examine the risk factors associated with foot complications, specifically amputation and fracture, in diabetic renal and combined renal/pancreas transplant recipients.
To identify patient characteristics and pre-transplant conditions that influence post-transplant foot health outcomes.

Main Methods:

Retrospective analysis of 340 diabetic renal and combined renal/pancreas transplant recipients.
Data collected between January 1985 and February 1995.
Evaluation of amputation and foot fracture rates in relation to various risk factors.

Main Results:

High rates of lower extremity amputation and foot fractures were observed across all studied groups.
Intact circulation and protective sensation were associated with better outcomes.
Smoking, prior amputation, and pre-transplant dialysis were identified as significant risk factors for post-transplant amputation.
Female recipients exhibited nearly double the fracture rate compared to males.
Concomitant pancreas transplantation did not substantially alter amputation or fracture risks.

Conclusions:

Diabetic transplant recipients are highly susceptible to foot complications, necessitating proactive management.
Modifiable factors like smoking cessation and pre-transplant health optimization are crucial for reducing amputation risk.
Gender and pre-transplant dialysis status are important considerations in assessing post-transplant foot complication risks.