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Determination of single-stranded oligodeoxynucleotides by capillary gel electrophoresis with laser induced
1University of Texas at Austin, College of Pharmacy, Division of Pharmaceutics 78712, USA.
Journal of Chromatography. A
|December 6, 1996
Abstract:
OliGreen reagent, a new dye for complexing of oligonucleotides of low molecular mass was successfully utilized for their quantitative analysis using on column derivatization and capillary gel electrophoresis with laser induced fluorescence. Method optimization for the precise, accurate and reproducible quantitation of low-molecular-mass oligonucleotides from aqueous matrices is described.