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Feto-maternal outcome in pre-eclampsia/eclampsia with and without multisystem organ failure managed by strict
1Department of Obstetrics and Gynaecology, Unitra, Transkei, South Africa.
To determine whether peripartum homeostasis can be maintained without invasive vascular monitoring, comparison of biological parameters in severe preeclampsia (PE)/eclampsia(E) with and without multisystem organ failure (MSOF) was done. Twenty six cases of severe PE/E with (n = 13) and without (n = 13) MSOF were managed with a strict input/output fluid regimen. Day one pre- and day one postdelivery haematology and blood chemistry were performed. MSOF was characterised by self-limiting hepato-renal failure and thrombocytopenia. Foetal demise was higher with MSOF (53.8%) than without (38.5%), but not significantly (chi-square = 0.62). Abruptio placentae was significantly more prevalent without (30.8%) than with MSOF (7.7%; chi-square = 5.54). Eclamptic seizures occurred at the same rate (46.2 and 30.8%; chi-square = 0.65) with both conditions. There was no maternal death. Without invasive vascular monitoring peripartum homeostasis can be achieved in severe PE/E with or without MSOF through a strict input/output regimen using Ringer's lactate.
To determine whether peripartum homeostasis can be maintained without invasive vascular monitoring, comparison of biological parameters in severe preeclampsia (PE)/eclampsia(E) with and without multisystem organ failure (MSOF) was done. Twenty six cases of severe PE/E with (n = 13) and without (n = 13) MSOF were managed with a strict input/output fluid regimen. Day one pre- and day one postdelivery haematology and blood chemistry were performed. MSOF was characterised by self-limiting hepato-renal failure and thrombocytopenia. Foetal demise was higher with MSOF (53.8%) than without (38.5%), but not significantly (chi-square = 0.62). Abruptio placentae was significantly more prevalent without (30.8%) than with MSOF (7.7%; chi-square = 5.54). Eclamptic seizures occurred at the same rate (46.2 and 30.8%; chi-square = 0.65) with both conditions. There was no maternal death. Without invasive vascular monitoring peripartum homeostasis can be achieved in severe PE/E with or without MSOF through a strict input/output regimen using Ringer's lactate.