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[Anatomopathological aspects of 25 cases of bilharzial bladder cancer]
1Laboratoire d'anatomie et de cytologie pathologiques, Faculté des Sciences de la Santé, BP 10896, Niamey, Niger.
Abstract:
The anatomopathology of 25 cases of bilharzial cancer is reported involving 20 men and 5 women. The macroscopic studies of the tumors revealed an unifocal, budding and infiltrating pattern. The significant type appeared to be the squamous carcinoma in 13 of the cases. All the 25 cases showed the presence of a bilharzial infestation with several patterns: tumoral clusters of squamous carcinoma and urothelial cells, clusters of scattered signet ring cells, elongated or undifferentiated atypical cells. The chronic inflammatory stroma contained bilharzia ova. The role played by metaplasia of the vesical urothelium is accepted by the majority of authors to explain the histogenesis of theses tumors.