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[Prognostic value of high FSH concentrations]
F Galtier-Dereure1, J Bringer, B Hédon
1Service d'Endocrinologie, CHU Montpellier.
Contraception, Fertilite, Sexualite (1992)
|September 1, 1996
Summary
Ovarian reserve, assessed by follicle-stimulating hormone (FSH) levels, impacts assisted reproductive technology success. Monitoring FSH variability may predict poor response, though test value needs further study.
Area of Science:
- Reproductive Endocrinology
- Infertility Research
Context:
- Ovarian reserve significantly influences assisted reproductive technology (ART) outcomes.
- Follicle-stimulating hormone (FSH) levels are key indicators of ovarian reserve.
- Ovarian aging precedes detectable clinical or endocrinological changes.
Purpose:
- To evaluate the utility of FSH measurement in assessing ovarian reserve for ART.
- To explore the correlation between FSH levels and ART cycle outcomes.
- To investigate the predictive value of FSH variability for poor ovarian response.
Summary:
- Plasma FSH concentration is a simple, accurate method for assessing ovarian reserve.
- FSH levels correlate with cancellation rates, oocyte yield, embryo quality, and pregnancy rates.
- Recurrent FSH monitoring and assessing intercycle variability can help predict poor ART response, even with normal baseline FSH.
Impact:
- Provides insights into optimizing ART protocols based on ovarian reserve.
- Highlights the potential of FSH variability as an early predictor of diminished ovarian response.
- Underscores the need for further research into the established value of ovarian reserve tests.