Creutzfeldt-Jakob disease in an Iranian: the first clinico-pathologically described case

This is the first report of a definite case of Creutzfeldt-Jakob disease in an Iranian and it has been confirmed by a neuropathological study and by the immunoelectrophoretic demonstration of PrP, the pathological amyloid protein specific to the spongiform encephalopathies. The clinical course and the topography and severity of brain pathology classify this case as of panencephalopathic type and support the view of different phenotypic expressions of CJD in relation to the existence of multiple strains of the causative agent.