[Practical experiences in the therapy of postweaning edema disease in piglets]

In a field trial 23 weeks old weaned piglets were orally inoculated with E. coli O139 K12 H1. The piglets received the same food and were kept under the same management regime. They were selected randomly into four groups and treated after the first clinical signs of CNS involvement of edema disease as follows during three days: Group 1: received a single daily i.m. application of 4 mg/kg body weight Melperone. Group 2: received a single daily i.m. application of 2 mg/kg body weight Amperozide. Group 3: was treated orally (intranasally) with 2 mg/kg body weight Amphetamin in a single daily application. Group 4: untreated control. The following parameters were evaluated before the begin of the therapy (day 0-4). A: Occurrence of diarrhea in a group B: Food consumption per piglet per day C: Death of piglets per group After the begin of the therapy (day 5-32) D: Death of piglets per group E: Average daily feed intake per piglet The results showed that the Melperone and Amphetamin treatment was superior regarding all examined parameters when compared to Amperozide treatment and to the control group.