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Alcohol in pharmaceutical products

G E Dukes, J G Kuhn, R P Evens

    American Family Physician
    |September 1, 1977
    PubMed
    Summary
    This summary is machine-generated.

    Many pharmaceutical products contain high alcohol concentrations, posing risks for patients undergoing specific therapies or with certain medical conditions. This hidden alcohol content complicates patient management and abstinence programs.

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    Area of Science:

    • Pharmacology
    • Patient Management

    Background:

    • Alcohol is a common diluent in over 500 pharmaceutical products, with concentrations reaching up to 68%.
    • The presence of alcohol in medications can lead to significant patient management challenges.

    Purpose of the Study:

    • To highlight the potential risks and complications associated with alcohol content in pharmaceutical products.
    • To inform healthcare providers about the implications for patient care, particularly for vulnerable populations.

    Main Methods:

    • Review of pharmaceutical product formulations to identify alcohol content.
    • Analysis of patient cases and medical conditions where alcohol in medications poses a risk.

    Main Results:

    • Over 500 proprietary products contain alcohol as a diluent, some at high concentrations (up to 68%).

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  • Specific patient groups, including those on disulfiram therapy, with peptic ulcers, or on CNS depressants, face increased risks.
  • Alcohol content complicates abstinence programs and poses challenges in addressing adolescent alcohol abuse.
  • Conclusions:

    • The significant alcohol content in numerous pharmaceuticals necessitates careful consideration in patient management.
    • Healthcare professionals must be aware of these risks to ensure patient safety and effective treatment.
    • Further attention is needed regarding the impact of pharmaceutical alcohol on addiction and abuse programs.