Related Experiment Video
Updated: Aug 14, 2026
Measuring Connectivity in the Primary Visual Pathway in Human Albinism Using Diffusion Tensor Imaging and Tractography
Published on: August 11, 2016
Analysis of the retinohypothalamic tract in congenic albino and pigmented rats
A M Miller1, R Chappell, W H Obermeyer
1University of Wisconsin-Madison, Neuroscience Training Program 53706, USA.
Abstract:
To determine whether differences in the retinohypothalamic tract (RHT) were related specifically to albinism, we analyzed the distribution and trajectory of this pathway in congenic F344-c/+ albino and pigmented rats using the inactive subunit of cholera toxin conjugated to horseradish peroxidase as an anterograde tracer. We found that the overall volume of the tract in the albino rats was greater than in the pigmented rats (P < 0.05). We also noted shape differences.
