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Related Experiment Videos

Magnesium: its role in cellular functions--a review

G Bronzetti, C Della Croce, T Davini

    Journal of Environmental Pathology, Toxicology and Oncology : Official Organ of the International Society for Environmental Toxicology and Cancer
    |January 1, 1995
    PubMed
    Summary

    Magnesium is vital for cell functions, and disruptions can cause diseases. This review covers magnesium

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    Area of Science:

    • Biochemistry and Molecular Biology
    • Cell Biology
    • Nutritional Science

    Background:

    • Magnesium is an essential mineral for numerous cellular processes.
    • Abnormal magnesium levels are linked to various pathological conditions.

    Purpose of the Study:

    • To review the multifaceted roles of magnesium in cellular functions.
    • To explore the impact of magnesium on the cell cycle, physiology, and disease.
    • To examine nutritional, toxicological, mutagenic, and carcinogenic aspects of magnesium.

    Main Methods:

    • Literature review and synthesis of existing research.
    • Analysis of studies on magnesium's effects on cell cycle regulation.
    • Examination of data on magnesium's physiological and pathological roles.

    Main Results:

    • Magnesium plays a critical role in cell cycle progression and regulation.
    • Nutritional status and toxicity influence magnesium's cellular impact.
    • Magnesium abnormalities are associated with mutagenesis and tumorigenesis.

    Conclusions:

    • Magnesium is indispensable for maintaining cellular health and function.
    • Dysregulation of magnesium homeostasis contributes significantly to disease development.
    • Further research into magnesium's role in pathology is warranted.

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