Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Hyperglycemia during childhood diarrhea

A Ronan1, A K Azad, O Rahman

  • 1Royal Children's Hospital, Melbourne, Victoria, Australia.

The Journal of Pediatrics
|January 1, 1997
PubMed
Summary

Childhood diarrhea can cause hyperglycemia due to a stress response to hypovolemia. This study found higher stress hormone levels in children with hyperglycemia and severe dehydration.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Sensitivity study on convective heat transfer in a driven cavity with star-shaped obstacle and hybrid nanofluid using response surface methodology.

Heliyon·2024
Same author

Artificial Neural Network analysis on the effect of mixed convection in triangular-shaped geometry using water-based Al2O3 nanofluid.

PloS one·2024
Same author

Artificial neural network (ANN) analysis on thermophysical properties of magnetohydrodynamics flow with radiation in an arc-shaped enclosure with a rotating cylinder.

Heliyon·2024
Same author

Performance evaluation of nanofluid-based photovoltaic thermal (PVT) system with regression analysis.

Heliyon·2024
Same author

Rotational effect of a cylinder on hydro-thermal characteristics in a partially heated square enclosure using CNT-water nanofluid.

Heliyon·2023
Same author

Assessing the hypolipidemic and gastro-liver protective activity of herbal combination with emphasis on PPI amid selected multiple antihypertensive drug combination in experimental animal models.

European review for medical and pharmacological sciences·2023

Area of Science:

  • Pediatrics
  • Endocrinology
  • Infectious Diseases

Background:

  • Hyperglycemia is a potential complication of childhood diarrhea.
  • The underlying mechanisms of hyperglycemia in this context require elucidation.

Purpose of the Study:

  • To investigate the cause of hyperglycemia in children experiencing diarrhea.
  • To identify factors associated with hyperglycemia in pediatric patients with diarrhea.

Main Methods:

  • Blood glucose levels were measured in children aged 2-10 years admitted with diarrhea.
  • Samples were analyzed for glucoregulatory hormones and gluconeogenic substrates in hyperglycemic and normoglycemic groups.
  • Patients were assessed for dehydration and specific infectious agents.

Main Results:

  • Hyperglycemia (blood glucose >10.0 mmol/L) was observed in 9.4% of pediatric diarrhea patients.
  • Hyperglycemic patients exhibited higher rates of severe dehydration and Vibrio cholerae/toxigenic E. coli infections.
  • Significantly elevated levels of epinephrine, norepinephrine, cortisol, glucagon, and C-peptide were found in hyperglycemic children.

Conclusions:

  • The stress response to hypovolemia is the primary cause of hyperglycemia in childhood diarrhea.
  • Severe dehydration and specific bacterial infections contribute to the development of hyperglycemia.

Related Experiment Videos