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Related Experiment Videos

Absorbable polyglycolide devices in trauma and bone surgery

N Ashammakhi1, P Rokkanen

  • 1Department of Orthopaedics and Traumatology, Helsinki University Central Hospital, Finland.

Biomaterials
|January 1, 1997
PubMed
Summary
This summary is machine-generated.

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Self-reinforcing poly(glycolic acid) (SR-PGA) implants offer strong internal fixation for bone fractures. These biocompatible, absorbable implants eliminate the need for removal surgery and associated risks.

Area of Science:

  • Biomaterials Science
  • Orthopedic Surgery
  • Polymer Chemistry

Background:

  • Poly(glycolic acid) (PGA), also known as hydroxyacetic acid, is a biocompatible polymer.
  • Self-reinforcing (SR) techniques allow the creation of strong PGA implants for orthopedic applications.

Purpose of the Study:

  • To evaluate the efficacy and safety of SR-PGA implants in internal bone fracture fixation.
  • To highlight the advantages of absorbable implants over traditional biostable ones.

Main Methods:

  • Routine clinical use of SR-PGA implants for internal fixation of bone fractures since 1984.
  • Extensive experimental animal studies to assess biocompatibility.

Main Results:

  • SR-PGA implants have been routinely used for fracture fixation since 1984.

Related Experiment Videos

  • Implants demonstrated biocompatibility in experimental studies.
  • A low incidence (1.7%) of sinus formation was observed in human cases, without affecting healing.

    • Conclusions:

    • SR-PGA implants are effective and biocompatible for internal bone fixation.
    • The use of these absorbable implants is justified due to the avoidance of a second removal surgery and associated risks.