Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Intra-operative nuclear medicine in surgical practice

A C Perkins1, J G Hardy

  • 1Department of Medical Physics, University Hospital, Queen's Medical Centre, Nottingham, UK.

Nuclear Medicine Communications
|December 1, 1996
PubMed
Summary

Radionuclide imaging and surgical probes effectively locate bone and soft tissue tumors during operations. This technique is the preferred method for osteoid osteoma excision, improving surgical accuracy.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Hybrid intraoperative imaging techniques in radioguided surgery: present clinical applications and future outlook.

Clinical and translational imaging·2017
Same author

Late Relapses in Hodgkin's Disease: Are They a Distinct Entity?

Leukemia & lymphoma·2016
Same author

Investigation of an SFOV hybrid gamma camera for thyroid imaging.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)·2016
Same author

The long history of the International Research Group in Immuno-Scintigraphy and Therapy (IRIST).

The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of...·2015
Same author

Measurement of gastric meal and secretion volumes using magnetic resonance imaging.

Physics in medicine and biology·2015
Same author

A scheme for assessing the performance characteristics of small field-of-view gamma cameras.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)·2014

Area of Science:

  • Nuclear medicine
  • Surgical oncology
  • Medical physics

Background:

  • The use of radionuclides for intra-operative tumor localization has grown significantly.
  • A review of over 15 years of experience with a mobile service utilizing a sterilizable probe system for localizing bone and soft tissue lesions in UK operating theaters was conducted.
  • The technique relies on the concentration of radiopharmaceuticals and a sterilizable detector system for surgical use.

Observation:

  • A sterilized nuclear probe with a 5 mm CdTe detector, coupled to a digital counter and ratemeter, was used in operating theaters.
  • A total of 68 surgical procedures were performed at 35 hospitals.
  • Fifty-eight patients had osteoid osteomas successfully excised, confirmed by histology.

Findings:

  • The technique proved successful in localizing various lesions including osteoid osteoma, osteoblastoma, hamartoma, Brodie's abscess, chronic bone infection, ectopic parathyroid adenoma, and metastatic neuroblastoma.

Related Experiment Videos

  • The method is considered the gold standard for surgical localization of osteoid osteoma.
  • Accurate pre-operative imaging is crucial for successful intra-operative lesion detection.

    • Implications:

    • The study confirms an expanding role for surgical probe-guided localization of primary and metastatic tumors.
    • This approach enhances the precision of tumor removal, potentially improving patient outcomes.
    • Further integration of radiopharmaceuticals and probe technology is expected in surgical oncology.