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[Chronic open angle glaucoma: correlation of pattern electroretinography and visual field indices]
B Neppert1, K Breidenbach, F Dannheim
1Universitäts-Augenklinik Lübeck.
Summary
Pattern electroretinogram (ERG) shows a marginal correlation with visual field defects in glaucoma patients. While useful for early detection, pattern ERG alone is insufficient for grading focal glaucomatous damage.
Area of Science:
- Ophthalmology
- Neuroscience
- Medical Imaging
Background:
- Pattern electroretinogram (ERG) is established for detecting early chronic open-angle glaucoma.
- Visual field defects are a key indicator of glaucoma progression.
Purpose of the Study:
- To investigate the correlation between pattern ERG amplitudes and specific visual field defects in glaucoma patients.
- To determine if pattern ERG can be used to grade focal glaucomatous damage.
Main Methods:
- Fifteen glaucoma patients with varying visual field defects were assessed using pattern ERG with specific stimulus parameters.
- Visual fields were analyzed using the Octopus 1-2-3 perimeter and PERIDATA system, focusing on localized and regional indices.
Main Results:
- A significant correlation (p<0.05) was found between pattern ERG amplitudes and the sector index (large checksizes, r=-0.58) and mean deviation in the 10-20 degree region (small checksizes, r=-0.538).
- A marginal correlation was observed between electrophysiological data and perimetric parameters.
Conclusions:
- Pattern ERG demonstrates a marginal correlation with visual field defects in glaucoma.
- The correlation may be influenced by combined diffuse and localized defects in glaucoma.
- Pattern ERG alone is not suitable for grading focal glaucomatous damage.