Related Experiment Videos
Biological studies of analogues of glucose iodinated in positions 1, 2, or 3
F Koumanov1, C Henry, C Ghezzi
1Laboratoire D'Etudes Des Radiopharmaceutiques, Groupe de Physiologie et Physiopatiologie Cellulaires Cardiaques, URA CNRS, La Touche, France.
Nuclear Medicine and Biology
|January 1, 1996
Abstract:
Analogues of glucose labeled with 123 iodine in positions 1, 2 or 3 have been synthesized. The aim of this study was to examine their biological behavior in four experimental models in order to assess whether they could be used to evaluate the uptake of glucose with single photon emission computed tomography (SPECT). The results obtained have shown that none of these molecules enters the cell using the glucose transporter. Therefore, they cannot be used as tracers of glucose uptake.